We often get questions about Ensembl VEP caches – the compressed data files we create for each new Ensembl release, which can be automatically installed with the VEP installer script – so here’s a quick introduction to these handy data bundles.
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Cool stuff the VEP can do: optimisation
Some Variant Effect Predictor (VEP) jobs are small, just ten or fewer variants, and that’s easy. Some VEP jobs are big, if you do variant calling on one whole human genome, that’s five million variants! The more variants you have, the more computing power the VEP needs to process them, which can make it slow. But there are ways to speed it up.