We are pleased to announce the release of Ensembl 113, and the corresponding release of Ensembl Genomes 60. This release brings major gene and regulatory feature annotation updates in Homo sapiens (Human) and Mus musculus (Mouse). We have updated existing genomes and added additional genomes across the different Ensembl sites, including livestock breeds in Ensembl, three new species in Ensembl Plants and 26 new species in Ensembl Metazoa. Can’t find the species you are looking for? Don’t forget that new and exciting genome assemblies and annotations are continuously added to Ensembl Rapid Release!
Continue readingWhat’s coming in Ensembl release 113 / Ensembl Genomes 60?
We expect to release Ensembl 113 and Ensembl Genomes 60 in September October 2024. Below is a list of updates that we are hoping to include in the upcoming release. However, please note that we cannot guarantee everything listed here will make it into the final release.
Cool stuff Ensembl VEP can do: supporting alternative human assemblies
The Ensembl VEP command-line tool can annotate and filter variants called against the latest human assemblies, including the telomere-to-telomere assembly of the CHM13 cell line (T2T-CHM13). In this blog post, we provide examples of how to run Ensembl VEP with these new assemblies and list the additional annotations supported via plugins.
Continue readingGetting to know us: Reham from Ensembl Havana
In July, we talked to Reham Fatima, a member of the Havana team. The Havana team carry out manual annotation on human, mouse, zebrafish and rat genomes. Reham has contributed to the MANE and GENCODE projects. Read more about Reham’s work at EMBL-EBI and what kind of cuisine she likes the most. You can also see some amazing photographs she has taken in her free time.
Continue readingUpdated gene annotation for Rattus norvegicus (Norway rat)
We have made updates to the Rattus norvegicus (Norway rat) gene annotation. The GRCr8 assembly is now the reference and mRatBN7.2 has been enhanced with manual annotation.
Continue readingGetting to know us: Ian Tsang (visiting PhD student)
Meet visiting PhD student Ian Tsang, who is doing a three-month work experience placement with the Ensembl Plants team. We talked all about his PhD, what projects he is working on during his time in Ensembl and what he does during his free time.
Continue readingIntegration of AlphaMissense scores into Ensembl
We’re excited to announce the integration of AlphaMissense pathogenicity scores into Ensembl! The display of AlphaMissense data in Ensembl and other EMBL-EBI resources aims to empower scientists to gain new insights, expand the exploration of genetic variation and the tolerance to change of different regions in proteins.
Continue readingEnsembl 112 has been released.
We are pleased to announce the release of Ensembl 112, and the corresponding release of Ensembl Genomes 59. We have some exciting new fish species, many more drosophila species and some incredible VEP updates.
Continue readingDowntime of Ensembl Genomes BLAST
Due to scheduled maintenance work, Ensembl Genomes BLAST will be temporarily unavailable on Tuesday 7th May 2024.
Continue readingGetting to know us: Swati from Ensembl Genebuild
We are back with our Getting to know us (a.k.a. Teamsembl) blog series after a short hiatus in March. For the month of April, we got the chance to Swati Sinha who is a senior bioinformatician in the Ensembl Genebuild team. The Genebuild team is in charge of the Ensembl automatic annotation pipeline. Read all about Swati and have a look at the amazing photographs she has taken during her travels.
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