The Ensembl VEP command-line tool can annotate and filter variants called against the latest human assemblies, including the telomere-to-telomere assembly of the CHM13 cell line (T2T-CHM13). In this blog post, we provide examples of how to run Ensembl VEP with these new assemblies and list the additional annotations supported via plugins.

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In July, we talked to Reham Fatima, a member of the Havana team. The Havana team carry out manual annotation on human, mouse, zebrafish and rat genomes. Reham has contributed to the MANE and GENCODE projects. Read more about Reham’s work at EMBL-EBI and what kind of cuisine she likes the most. You can also see some amazing photographs she has taken in her free time.

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